Summary of Product Characteristics
last updated on the eMC:
26/06/2008
When a pharmaceutical company changes an SPC or PIL, a new version is published on the eMC. For each version, we show the dates it was published on the eMC and the reasons for change.
Updated on 26/06/2008 and displayed until Current
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Reasons for adding or updating:
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Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
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| Date of revision of text on the SPC: 01-Feb-2008 |
| Legal Category: POM |
| Black Triangle (CHM):
NO |
Free-text change information supplied by the pharmaceutical company
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The only change is to section 4.5 'Interactions with medicinal products and other forms of interactions' where a statement on SSRIs has been added. See below:
Potentiated systemic beta-blockade (e.g. decreased heart rate, depression) has been reported during combined treatment with CYP2D6 inhibitors (e.g. quinidine, SSRIs) and timolol. ,possibly because quinidine inhibits the metabolism of timolol via the P-450 enzyme, CYP2D6..
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Updated on 27/04/2007 and displayed until 26/06/2008
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Change to section 1 -Name of the Medicinal product
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| Date of revision of text on the SPC: 03/2007 |
| Legal Category: POM |
| Black Triangle (CHM):
NO |
Free-text change information supplied by the pharmaceutical company
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Section 1 Name of Product
Timoptol Unit Dose Ophthalmic Solution 0.25% & 0.5% will now be called Timoptol Unit Dose 0.25% & 0.5% w/v Eye Drops Solution
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Updated on 10/06/2002 and displayed until 27/04/2007
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Change to section 4.8 - Undesirable Effects
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Updated on 16/08/2001 and displayed until 10/06/2002
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Transferred from eMC version 1
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Updated on 16/08/2001 and displayed until 16/08/2001
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Transferred from eMC version 1
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Updated on 18/04/2001 and displayed until 16/08/2001
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Updated on 06/09/1999 and displayed until 18/04/2001
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